Author

Noah A. Smith

ORCID 0000-0002-2310-6380Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Organism:non-human primate· 1 Approach:statistical model· 1

Frequent Co-Authors

Amiel R Hudley· 1 shared Beverly L. DavidsoniD· 1 shared Bryan P. SimpsoniD· 1 shared Christopher M. Fluta· 1 shared Christopher P. CaliiD· 1 shared David E. LeibiD· 1 shared George J. Yohrling· 1 shared Icnelia Huerta-Ocampo· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Amiel R Hudley

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1 paper

Recent·Most cited

Computational modeling and preclinical validation support targeting somatic instability for Huntington's disease treatment

Bryan P. Simpson, Paul T. Ranum, David E. Leib, Luis Tecedor, Ryan C Giovenco, Icnelia Huerta-Ocampo, Amiel R Hudley, Noah A. Smith, Christopher M. Fluta, Christopher P. Cali, Jamie D. Benoit, Jenna Carroll Soper, John Connelly, George J. Yohrling, Paiman Peter Ghoroghchian, , Beverly L. Davidson

The paper develops a computational model to predict therapeutic benefits of reducing somatic instability in Huntington's disease and validates it with preclinical experiments.

Nature Communications · Oct 28, 2026Peer-reviewedNeuroscience