Author

Gary W. Reuther

Moffitt Cancer CenterORCID 0000-0002-2317-931XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Garima PandeyiD· 1 shared Lucia MazzacuratiiD· 1 shared Narmin E. AminiD· 1 shared Tegan M. Rowsell· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperCancer Biology

Garima PandeyORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintAug 20, 2026

Modulation of the sensitivity to ruxolitinib-mediated JAK2 inhibition by mutationally activated SHP2 exhibits cell context dependency in pre-clinical models of myeloproliferative neoplasms

Tegan M. Rowsell, Garima Pandey, Lucia Mazzacurati…·Gary W. Reuther

This study shows that an activating SHP2 mutation in MPN cell models alters sensitivity to JAK2 inhibition, with context-dependent effects observed in different cell lines.

DOI 10.64898/2026.08.19.744423

humanbulk RNA-seq

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