NeuroscienceActa Neuropathologica CommunicationsPeer-reviewed
Human TDP-43 overexpression in zebrafish motor neurons triggers MND-like phenotypes through gain-of-function mechanism
Alison L. Hogan, Madison A. Kane, Patrick Chiu…·Marco Morsch
This study uses zebrafish models to show that human TDP-43 overexpression in motor neurons causes MND-like phenotypes through gain-of-function mechanisms, with distinct effects based on TDP-43 variant.
5 citations