Author

Madison A. Kane

Macquarie UniversityORCID 0000-0002-3982-1282Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Organism:zebrafish· 1

Frequent Co-Authors

Alison L. HoganiD· 2 shared Cindy MaureliD· 2 shared Ian P. BlairiD· 2 shared Marco MorschiD· 2 shared Patrick Chiu· 2 shared Sharlynn WuiD· 2 shared Adam K. WalkeriD· 1 shared Albert LeeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersNeuroscience

Alison L. HoganORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintJul 25, 2026

SFPQ dysregulation promotes TDP-43 pathology through a pathogenic feedback loop

Alison L. Hogan, Patrick Chiu, Natalie Grima…·Marco Morsch

This study identifies SFPQ as a contributor to TDP-43 pathology through a bidirectional feedback loop, showing SFPQ dysregulation drives TDP-43 mislocalization and aggregation.

DOI 10.64898/2026.07.22.740184

𝕏 PostBluesky

NeuroscienceActa Neuropathologica CommunicationsPeer-reviewedDec 2, 2025

Human TDP-43 overexpression in zebrafish motor neurons triggers MND-like phenotypes through gain-of-function mechanism

Alison L. Hogan, Madison A. Kane, Patrick Chiu…·Marco Morsch

This study uses zebrafish models to show that human TDP-43 overexpression in motor neurons causes MND-like phenotypes through gain-of-function mechanisms, with distinct effects based on TDP-43 variant.

5 citations

zebrafishexperimental assay

𝕏 PostBluesky