Author

Patrick Chiu

Macquarie University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Organism:zebrafish· 1

Frequent Co-Authors

Alison L. HoganiD· 2 shared Cindy MaureliD· 2 shared Ian P. BlairiD· 2 shared Madison A. KaneiD· 2 shared Marco MorschiD· 2 shared Sharlynn WuiD· 2 shared Adam K. WalkeriD· 1 shared Albert LeeiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersNeuroscience

Alison L. HoganORCID

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2 papers

Recent·Most cited

SFPQ dysregulation promotes TDP-43 pathology through a pathogenic feedback loop

Alison L. Hogan, Patrick Chiu, Natalie Grima, Sharlynn Wu, Grant Richter, Cindy Maurel, Madison A. Kane, Andrew Smith, Shu Yang, Adam K. Walker, Ian P. Blair, Marco Morsch

This study identifies SFPQ as a contributor to TDP-43 pathology through a bidirectional feedback loop, showing SFPQ dysregulation drives TDP-43 mislocalization and aggregation.

bioRxiv · Jul 25, 2026 · PreprintNeuroscience

Human TDP-43 overexpression in zebrafish motor neurons triggers MND-like phenotypes through gain-of-function mechanism

Alison L. Hogan, Madison A. Kane, Patrick Chiu, G. Richter, Cindy Maurel, Sharlynn Wu, Natalie M. Scherer, Emily K. Don, Albert Lee, Ian P. Blair, Roger S. Chung, Marco Morsch

This study uses zebrafish models to show that human TDP-43 overexpression in motor neurons causes MND-like phenotypes through gain-of-function mechanisms, with distinct effects based on TDP-43 variant.

Acta Neuropathologica Communications · Dec 2, 2025Peer-reviewedNeuroscience