Vítor A. P. Martins dos Santos

This study identifies clarithromycin as a potential therapeutic for inflammatory bowel disease through in-silico drug repositioning and experimental validation of its effects on NF-κB signaling.

The paper develops a genome-scale metabolic model of a co-culture of Clostridium autoethanogenum and Clostridium kluyveri to optimize syngas conversion to medium-chain fatty acids.

This study compares the pathogenicity of Staphylococcus aureus and Streptococcus pyogenes isolates toward human myoblasts and keratinocytes, finding higher internalization and cytotoxicity by NSTI-SA in myoblasts.

The paper identifies a fungal citrate exporter in Aspergillus niger by comparing gene expression under different citrate-producing conditions and validating its function in yeast and the fungus itself.

The paper analyzes the correlation between 16S-rRNA phylogeny and protein domain content in bacterial genomes to assess functional diversity and its relationship with evolutionary distance.

The paper presents a revised human metabolic model that accurately incorporates flavin cofactors, improving predictions of metabolic impacts and biomarkers in flavoproteome-related diseases.