Author

Zhibin Chen

Hainan Medical UniversityORCID 0000-0002-2354-6589Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Organism:C. elegans· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Auden Cote-L’Heureux· 1 shared Benjamin Vyshedskiy· 1 shared Cera W. HassinaniD· 1 shared Dori C. WoodsiD· 1 shared Douglass M. TurnbulliD· 1 shared Irini TopalidouiD· 1 shared Jihong BaiiD· 1 shared Jonathan L. TillyiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Auden Cote-L’Heureux

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2 papers

Recent·Most cited

A novel, wave-shaped profile of germline selection of pathogenic mtDNA mutations is discovered by bypassing a classical statistical bias.

Melissa Franco, Auden Cote-L’Heureux, Zoë Fleischmann, Zhibin Chen, Mark Khrapko, Benjamin Vyshedskiy, Maxim Braverman, Konstantin Yu. Popadin, Sarah J. Pickett, Dori C. Woods, Jonathan L. Tilly, Douglass M. Turnbull, Konstantin Khrapko

This paper reveals a wave-shaped germline selection profile of mtDNA mutations by correcting for regression to the mean bias, showing how mutations are filtered in the germline.

bioRxiv · Nov 21, 2023 · PreprintGenomics

Dopamine receptor DOP-1 engages a sleep pathway to modulate swimming in C. elegans

Ye Xu, Lin Zhang, Yan Liu, Irini Topalidou, Cera W. Hassinan, Michael Ailion, Zhenqiang Zhao, Tan Wang, Zhibin Chen, Jihong Bai

This study identifies a pathway linking the dopamine receptor DOP-1 to a sleep mechanism that modulates sustained swimming in C. elegans.

iScience · Mar 1, 2021Peer-reviewedGenetics