Author

Robert J. Williams

University of BathORCID 0000-0002-2369-1989Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:ChIP-seq· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Giuseppina PisignanoiD· 1 shared Ioanna PavlakiiD· 1 shared Jelena M. TeleniusiD· 1 shared Jim R. HughesiD· 1 shared Julia SeroiD· 1 shared Katriona L. HoleiD· 1 shared Keith W. VanceiD· 1 shared Michael ShapiroiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenomics

Giuseppina PisignanoORCID

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2 papers

Recent·Most cited

NeuroscienceMolecular NeurobiologyPeer-reviewedDec 14, 2023

Epigallocatechin Gallate Modulates Microglia Phenotype to Suppress Pro-Inflammatory Signalling Cues and Inhibit Phagocytosis

Philip L. Regan, Katriona L. Hole, Julia Sero, Robert J. Williams

This study shows that EGCG modulates microglia to reduce inflammation and phagocytosis of Aβ, suggesting therapeutic potential for AD.

8 citations

bulk RNA-seqstatistical model

𝕏 PostBluesky

GenomicsPLoS GeneticsPeer-reviewedJun 16, 2022

Chromatin interaction maps identify Wnt responsive cis-regulatory elements coordinating Paupar-Pax6 expression in neuronal cells

Ioanna Pavlaki, Michael Shapiro, Giuseppina Pisignano…·Keith W. Vance

The paper identifies Wnt-responsive cis-regulatory elements that coordinate Paupar-Pax6 expression in neuronal cells through chromatin interactions.

13 citations

𝕏 PostBluesky