Julia Sero

Colorectal cancer progression to metastasis is associated with dynamic genome-wide biphasic 5-hydroxymethylcytosine accumulation.

This study shows that 5-hydroxymethylcytosine (5hmC) levels increase in liver metastases compared to primary colon tumors and is linked to TET2/TET3 expression and migration-related pathways.

Epigallocatechin Gallate Modulates Microglia Phenotype to Suppress Pro-Inflammatory Signalling Cues and Inhibit Phagocytosis

This study shows that EGCG modulates microglia to reduce inflammation and phagocytosis of Aβ, suggesting therapeutic potential for AD.

Identification of phenotype-specific networks from paired gene expression-cell shape imaging data

The paper integrates gene expression and cell shape imaging data to identify phenotype-specific gene networks and signaling pathways involved in breast cancer cell morphology.