Cancer BiologybioRxivPreprint
Acute Myeloid Leukemia Relapse after Bromodomain Inhibitor Treatment or Chemotherapy is Characterized by Myc-Ras Transcriptional Remodeling
Benjamin J. Huang, Jeevitha D’Souza, Alexa Rane Batingana…·Kevin Shannon
This study shows that AML relapse after BET inhibitor or chemotherapy involves Myc-Ras transcriptional changes, highlighting transcriptional plasticity in relapsed leukemias.
DOI 10.1101/2025.11.13.688312