Author

Jeevitha D’Souza

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Alexa Rane Batingana· 2 shared Benjamin J. HuangiD· 2 shared Kevin ShannoniD· 2 shared Soheil MeshinchiiD· 2 shared Abigail S. Lin· 1 shared Adam J. LambleiD· 1 shared Aishwarya C. Ballapuram· 1 shared Alexander LossosiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersCancer Biology

Alexa Rane Batingana

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Acute Myeloid Leukemia Relapse after Bromodomain Inhibitor Treatment or Chemotherapy is Characterized by Myc-Ras Transcriptional Remodeling

Benjamin J. Huang, Jeevitha D’Souza, Alexa Rane Batingana, Max Harris, Xinyue Wang, Eugene Hwang, Anica M. Wandler, Michael R. Burgess, Qing Li, Soheil Meshinchi, Gideon E. Bollag, Kevin Shannon

This study shows that AML relapse after BET inhibitor or chemotherapy involves Myc-Ras transcriptional changes, highlighting transcriptional plasticity in relapsed leukemias.

bioRxiv · Nov 13, 2025 · PreprintCancer Biology

TP53 Inactivation Confers Resistance to the Menin Inhibitor Revumenib in Acute Myeloid Leukemia

Jeevitha D’Souza, Camille J. Leung, Aishwarya C. Ballapuram, Abigail S. Lin, Alexa Rane Batingana, Adam J. Lamble, Rhonda E. Ries, Carolina E. Morales, Charisa Cottonham, Pranav Gona, Li Fan, Xiaotu Ma, Kevin Shannon, Soheil Meshinchi, Benjamin S. Braun, Benjamin J. Huang

This study shows TP53 mutations cause resistance to revumenib in AML and suggests combining MCL-1 inhibitors with menin inhibitors could be effective.

bioRxiv · Mar 24, 2025 · PreprintCancer Biology

A new drug candidate for glycogen storage disorders enhances glycogen catabolism: Lessons from Adult Polyglucosan Body Disease models

Hilla Vaknin, Kumudesh Mishra, Jeevitha D’Souza, Monzer Marisat, Uri Sprecher, Shane Wald-Altman, Anna Dukhovny, Yuval Raviv, Benny Da’adoosh, Hamutal Engel, Sandrine Benhamron, Keren Nitzan, Anna Permyakova, Hanna Rosenmann, Alexander Lossos, , Miguel Weil

This study demonstrates that 144DG11 improves survival and motor function in APBD mouse models by promoting autophagic glycogen catabolism through LAMP1 interaction.

bioRxiv · Mar 18, 2021 · PreprintNeuroscience