Sean Mackey

Intracranial electrophysiology reveals distinct neural representations of nociception and salience in the human brain

The paper uses intracranial recordings to show that nociception and salience have distinct neural representations in the human brain, with different anatomical, temporal, and functional characteristics.

CREST: A Cortical Resting-State EEG Spatial Transformer for Chronic Pain Inference

The paper uses resting-state EEG data and a spatial transformer model to classify chronic pain status with an AUROC of 0.782.

Opioid- and NMDA-receptor-dependent neural plasticity mediates long-term analgesia from motor cortical stimulation

This study shows that motor cortical stimulation induces long-term pain relief through opioid and NMDA-receptor-dependent neural plasticity in the rostral ventromedial medulla.

Differential encoding of noxious heat and self-reported pain along corticospinal networks: a simultaneous spinal cord-brain fMRI study

This study uses simultaneous spinal cord-brain fMRI to show how nociceptive stimuli and pain perception are encoded in corticospinal networks, with spinal cord activity primarily reflecting stimulus temperature.

EPISeg: Automated segmentation of the spinal cord on echo planar images using open-access multi-center data

The paper introduces EPISeg, a deep learning model for automated spinal cord segmentation on gradient-echo EPI data, showing improved performance over existing methods.

Body size interacts with the structure of the central nervous system: A multi-center in vivo neuroimaging study

This study shows body size parameters significantly correlate with brain and spinal cord MRI metrics and should be included in neuroimaging studies.

Mapping Hand Function with Simultaneous Brain-Spinal Cord Functional MRI

This study uses simultaneous brain-spinal cord fMRI to map neural activity related to hand strength and dexterity, revealing graded activation and inhibition patterns across motor and sensory regions.