Alyssa M. Pivirotto

Correcting for Global Synonymous Selection Improves the Accuracy of Episodic Positive Selection Inference

This paper shows that accounting for global synonymous selection improves the accuracy of detecting episodic positive selection in protein evolution.

Allele age estimators designed for whole genome datasets show only a moderate reduction in performance when applied to whole exome datasets

The paper evaluates allele age estimators on whole exome datasets and finds a moderate performance decrease compared to whole genome data.

A new comparative framework for estimating selection on synonymous substitutions.

The paper develops MSS models to estimate selection on synonymous substitutions, finding significant correlations with covariates of codon usage selection across Drosophila species.