Vitor Antonio Corrêa Pavinato

The paper estimates the evolutionary fitness of all synonymous codon changes in Drosophila melanogaster using polymorphism data, finding weak but significant selection on codon usage.

The paper introduces a new method to estimate mutation fitness effects by analyzing site frequency ratios, showing weak selection on synonymous sites in Drosophila populations.

The paper develops MSS models to estimate selection on synonymous substitutions, finding significant correlations with covariates of codon usage selection across Drosophila species.

The paper expands the stdpopsim species catalog and improves genome simulations by adding non-crossover recombination and species-specific annotations, making simulations more realistic for non-model organisms.