BiochemistrybioRxivPreprint
EGFR-targeted antisense oligonucleotides modified with boron clusters offer an innovative approach to cancer chemo-radiotherapy
Damian Kaniowski, Katarzyna Ebenryter‐Olbińska, Justyna Suwara…·Barbara Nawrot
This paper demonstrates that B-ASOLNA-CHOL, a boron cluster-conjugated antisense oligonucleotide, enhances cancer cell uptake and cytotoxicity when combined with radiotherapy, reducing tumor size in xenograft models.
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