Author

Yunyue Wang

Columbia UniversityORCID 0000-0002-2421-5087Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Brian J. LeeiD· 2 shared Shan ZhaiD· 2 shared Angelina Li· 1 shared Antony B. HolmesiD· 1 shared Baek KimiD· 1 shared Demis MenolfiiD· 1 shared Faye Yan· 1 shared Hanwen ZhangiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenetics

Brian J. LeeORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintAug 11, 2026

Programmed Clonal Expansion Drives an ATM-Dependent Vulnerability Underlying Preferential Lymphocyte Depletion and Myeloid Bias Following DNA Damage

Katherine H Lee, Zhengping Shao, Yunyue Wang…·Shan Zha

The paper identifies programmed clonal expansion during V(D)J recombination as an ATM-dependent vulnerability causing preferential lymphocyte depletion and myeloid bias after DNA damage.

DOI 10.64898/2026.08.05.743027

mousebulk RNA-seq

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GeneticsNature CommunicationsPeer-reviewedJun 19, 2023

ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion.

Demis Menolfi, Brian J. Lee, Hanwen Zhang…·Shan Zha

This study shows ATR kinase prevents replication resource exhaustion in early S phase, supporting normal cell proliferation by regulating origin firing.

40 citations

mouseexperimental assay

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