Author

Fabio Ciccarone

University of Rome Tor VergataORCID 0000-0002-2425-2240Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alessio Vecchio· 1 shared Claudio SetteiD· 1 shared Consuelo PitolliiD· 1 shared Federica Di SanoiD· 1 shared Federica RossiniD· 1 shared Fiorella ColasuonnoiD· 1 shared Luca OcchigrossiiD· 1 shared Manuela D’ElettoiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Alessio Vecchio

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1 paper

Recent·Most cited

Epigenetic modulation of RIPK3 by Transglutaminase 2-dependent serotonylation of H3K4me3 affects necroptosis

Alessio Vecchio, Fiorella Colasuonno, Luca Occhigrossi, Consuelo Pitolli, Veronica Bellanca, Fabio Ciccarone, Manuela D’Eletto, Federica Di Sano, Vittoria Pagliarini, Claudio Sette, Mauro Piacentini, Federica Rossin

This study shows that Transglutaminase 2 (TG2) promotes necroptosis by serotonylating H3K4me3 at the Ripk3 promoter, preventing its methylation and enabling Ripk3 expression.

Cellular and Molecular Life Sciences · Apr 9, 2025Peer-reviewedCell Biology