Barcoded Rational AAV Vector Evolution enables systematic in vivo mapping of peptide binding motifs
Marcus Davidsson, Gang Wang, Patrick Aldrin-Kirk, Tiago Cardoso, Sara Nolbrant, Morgan Hartnor, Janitha M. Mudannayake, Malin Parmar, Tomas Björklund
The paper introduces BRAVE, a method for rational AAV vector evolution that maps peptide binding motifs in vivo using barcoding and clustering.
Proceedings of the National Academy of Sciences · Dec 9, 2019Peer-reviewedNeuroscience