Author

Tomas Björklund

Lund UniversityORCID 0000-0001-7968-0034Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:non-human primate· 1 Research Focus:protein design· 1 Assay:proteomics· 1

Frequent Co-Authors

Marcus DavidssoniD· 3 shared Alexander SvanbergssoniD· 1 shared Ariel A. HippeniD· 1 shared Åsa PeterséniD· 1 shared Brian M. Kelly· 1 shared Caroline HaikaliD· 1 shared Di LiuiD· 1 shared Edoardo Brandi· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersNeuroscience

Marcus DavidssonORCID

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Author profile →

4 papers

Recent·Most cited

NeuroscienceMolecular TherapyPeer-reviewedDec 10, 2025

Administration of barcoded AAV capsid library to the putamen of non-human primates identifies variants with efficient retrograde transport

Yulia Dzhashiashvili, Jodi L. McBride, Emily B. Fabyanic…·Tomas Björklund

The paper tests AAV capsid variants in non-human primates to identify those with improved retrograde transport properties.

1 citation

non-human primatebulk RNA-seq

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NeurosciencebioRxivPreprintMar 4, 2023

Mutant huntingtin expression in the hypothalamus promotes ventral striatal neuropathology

Rana Soylu-Kucharz, Natalie Adlesic, Marcus Davidsson…·Åsa Petersén

This study shows that mutant huntingtin in the hypothalamus causes ventral striatal neuropathology, including DARPP-32 neuron loss, and disrupts hypothalamus-ventral striatal circuitry in HD mice.

DOI 10.1101/2023.03.04.530949

mouseexperimental assay

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Molecular BiologyNeurotherapeuticsPeer-reviewedJul 1, 2021

FRET-based screening in HEK293T identifies p38 MAPK and PKC inhibition as therapeutic targets for α-synuclein aggregation

Alexander Svanbergsson, Fredrik Ek, Isak Martinsson…·Jiayi Li

8 citations

humanexperimental assay

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NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedDec 9, 2019

Barcoded Rational AAV Vector Evolution enables systematic in vivo mapping of peptide binding motifs

Marcus Davidsson, Gang Wang, Patrick Aldrin-Kirk…·Tomas Björklund

The paper introduces BRAVE, a method for rational AAV vector evolution that maps peptide binding motifs in vivo using barcoding and clustering.

142 citationstop 1%

mouseproteomics

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