ImmunologybioRxivPreprint
A genetic screen to identify deubiquitinases as regulators of IRF7
Shumin Fan, Pracheta Sengupta, Karan Chawla…·Saurabh Chattopadhyay
The paper identifies USP2 and OTUD5 as deubiquitinases regulating IRF7 activity through distinct ubiquitination mechanisms, impacting antiviral immunity.
DOI 10.1101/2025.09.09.675186