Host genetic variants regulates CCR5 expression on immune cells: a study in people living with HIV and healthy controls
Jéssica Cristina dos Santos, Zhenhua Zhang, Louise E. van Eekeren, Ezio T. Fok, Nadira Vadaq, Lisa Van de Wijer, Wouter A. van der Heijden, Valerie A. C. M. Koeken, Hans J. P. M. Koenen, Musa M. Mhlanga, Mihai Gheorghe Netea, André J. A. M. van der Ven, Yang Li
This study identifies genetic variants influencing CCR5 expression on immune cells in HIV-positive and healthy individuals, showing cell-specific regulation and effects on inflammatory mediators.
bioRxiv · Jun 19, 2022 · PreprintSystems Biology