Musa M. Mhlanga

This study investigates the role of PKCδ in macrophage immunomodulation during Mtb infection, finding that its deficiency leads to increased Mtb burden and exacerbated pathology.

This study identifies genetic variants influencing CCR5 expression on immune cells in HIV-positive and healthy individuals, showing cell-specific regulation and effects on inflammatory mediators.

This study identifies associations between rare and common genetic variants in the IL-1 pathway and cytokine responses to various stimuli in healthy individuals.

DypFISH quantitatively investigates spatial and temporal subcellular localization of RNA and protein using micropatterning and fluorescence microscopy, revealing reproducible patterns and dynamics.

The paper identifies transcriptionally induced enhancers in macrophages infected with Mycobacterium tuberculosis and links them to immune gene activation.

This study shows HIV-1 evades apoptosis in macrophages by manipulating the MAP2K1/ERK2 pathway to dysregulate lincRNA-p21, and suggests MAP2K1/ERK2 inhibitors as a therapeutic strategy.

The paper identifies transcribed enhancers in mouse macrophages during activation and shows their association with gene expression and inflammation-related transcription factors.