Jonathan C. Mcleod

Dynamic proteomic profiling reveals protein-specific regulation of synthesis rates underpinning the divergent adaptation of human muscle to endurance and resistance training

This study identifies protein-specific synthesis rate changes in human muscle under endurance and resistance training, revealing mode-specific adaptations in subcellular protein subsets.

A network-based atlas of human skeletal muscle aging

This paper develops a network-based atlas of human skeletal muscle aging using transcriptomic data from 1,675 biopsies and multiple single-cell technologies, revealing gene modules and interactions associated with aging and load status.

Network-based modelling reveals cell-type enriched patterns of non-coding RNA regulation during human skeletal muscle remodelling

The paper identifies ncRNA genes regulated during skeletal muscle hypertrophy in 144 individuals using transcriptomic analysis and network modelling.