Author

Axel Loewe

Karlsruhe Institute of TechnologyORCID 0000-0002-2487-4744Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:electrophysiology· 1 Organism:human· 1 Organism:rat· 1 Research Focus:software / tool· 1 Approach:statistical model· 1

Frequent Co-Authors

Moritz LinderiD· 2 shared Anton J. PrassliD· 1 shared Aurel NeiciD· 1 shared Callum Michael Zgierski-JohnstoniD· 1 shared Christoph M. AugustiniD· 1 shared Edward Joseph VigmondiD· 1 shared Elias KarabelasiD· 1 shared Eva A. Rog‐ZielinskaiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

Moritz LinderORCID

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3 papers

Recent·Most cited

Cardiomyocyte mechanical activity counteracts intraluminal calcium depletion in the transverse-axial tubular system during fast electrical stimulation

Sofía Orós-Rodrigo, Jiaying Fu, Joachim Greiner, Josef Madl, Moritz Linder, Callum Michael Zgierski-Johnston, A Loewe, Peter Karl Kohl, Eva A. Rog‐Zielinska

bioRxiv · Jan 10, 2026 · PreprintCell Biology

Sympathetic Stimulation Can Compensate for Hypocalcaemia-Induced Bradycardia in Human and Rabbit Sinoatrial Node Cells

Moritz Linder, Tomáš Starý, Gergő Bitay, Norbert Nagy, Axel Loewe

This study extends SANC models with β-AR signaling to show that sympathetic stimulation can compensate for hypocalcaemia-induced bradycardia in human and rabbit cells.

The Journal of Physiology · Feb 27, 2025Peer-reviewedCell Biology

The openCARP Simulation Environment for Cardiac Electrophysiology

Gernot Plank, Axel Loewe, Aurel Neic, Christoph M. Augustin, Yung-Lin Huang, Matthias A. F. Gsell, Elias Karabelas, Mark Nothstein, Anton J. Prassl, Jorge Sánchez, Gunnar Seemann, Edward Joseph Vigmond

The paper introduces openCARP, an open-source simulation environment for cardiac electrophysiology, and describes its capabilities and potential to improve reproducibility and standardization in the field.

Computer Methods and Programs in Biomedicine · Jun 7, 2021Peer-reviewedBioinformatics