A Cohort-Based Global Sensitivity Benchmark of MRI-Derived Whole-Heart Electromechanical Models in Healthy Hearts
Shahrokh Rahmani, Jim Pouliopoulos, Angela Lee, Rosie K. Barrows, José Alonso Solís-Lemus, Marina Strocchi, Cristóbal Rodero, Abdul Qayyum, S. Samaneh Lashkarinia, Caroline H. Roney, Christoph M. Augustin, Gernot Plank, Diane Fatkin, Andrew Jabbour, Steven Niederer
The paper benchmarks global sensitivity analysis of whole-heart electromechanical models across five healthy subjects, finding haemodynamic parameters dominate cardiac function despite anatomical variation.
bioRxiv · Mar 30, 2026 · PreprintSystems Biology