ImmunologybioRxivPreprint
Asparagine availability differentially regulates early vs late CD4+ and CD8+ T cell activation, metabolism and autophagy
Mingcheng Song, Linda V. Sinclair, Mary J. Tozer…·Robert J. Salmond
This study shows CD4+ T cells rely more on asparagine uptake than CD8+ T cells for activation, differentiation, metabolism, and autophagy, with CD8+ cells expressing more ASNS.
DOI 10.64898/2026.04.27.721062