Bridgette D. Semple

This study investigates the long-term effects of Klebsiella pneumoniae infection following traumatic brain injury in mice, finding no significant impact on neurobehavioral outcomes or seizure development.

This study shows that LPS treatment after TBI causes acute neuroinflammation and gut microbiome changes but does not affect long-term outcomes.

This study reviews preclinical blood biomarkers for traumatic brain injury, finding that NfL and GFAP show promise for prognosis and pharmacodynamic studies.

This study shows that repeated mild traumatic brain injuries (rmTBI) cause time- and location-dependent changes in cranial bone structure in rats, specifically increasing bone thickness and reducing marrow cavity volume in the interparietal bone.

This study shows that acute treatment with TrkB agonist LM22A-4 after pediatric TBI reduces tissue damage and preserves myelin integrity, with some behavioral improvements.