ImmunologybioRxivPreprint
Glycoengineering of the hepatitis C virus E2 glycoprotein leads to improved biochemical properties and enhanced immunogenicity
Liudmila Kulakova, Kiki H. Li, Austin W.T. Chiang…·Thomas R. Fuerst
This study shows that glycoengineering of HCV E2 glycoprotein affects antigen biochemical properties and immune response, with some glycans improving neutralization potency.
DOI 10.1101/2025.04.02.646860