Author
Institute for Bioscience and Biotechnology Research
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
Liudmila Kulakova, Sarah Jeong, Dong-Xiu Zhang…·Thomas R. Fuerst
This paper develops a nanoparticle vaccine platform incorporating native HCV E1E2 to enhance immunogenicity, showing improved neutralizing antibody responses compared to subunit vaccines.
Linling He, Yi-Zong Lee, Yi-Nan Zhang…·Jiang Zhu
The paper designs, characterizes, and tests a soluble HCV E1E2 heterodimer and self-assembling nanoparticles for vaccine development.
Harry T. Paul, Jessica L. Mimms, Hanna Aboueid…·Justin R. Bailey
The paper isolates E1-dependent broadly neutralizing antibodies against HCV and uses mAbClust with AlphaFold 3 to map a quaternary epitope spanning E1 and E2.
Fang Chen, Erick Giang, Padmaja Natarajan…·Mansun Law
This study shows that B cells in hepatitis C patients retain dysregulated transcriptional profiles after cure, with sustained TNF signaling driving chronic inflammation and loss of protective memory.
Liudmila Kulakova, Kiki H. Li, Austin W.T. Chiang…·Thomas R. Fuerst
This study shows that glycoengineering of HCV E2 glycoprotein affects antigen biochemical properties and immune response, with some glycans improving neutralization potency.