Gabrielle L. Turvey

This paper shows that AURKB drives the dissolution of CIZ1-RNA assemblies from the inactive X chromosome during mitosis by phosphorylating CIZ1's C-terminal extensions, disrupting its RNA interactions.

The paper shows that elevated CIZ1 C-terminal anchor domain in early-stage breast cancers disrupts nuclear RNA assemblies, leading to chromatin deprotection and gene expression changes.