A Genome-wide CRISPR screen unveils the endosomal maturation protein WDR91 as a promoter of productive ASO activity in melanoma
Grégory Menchon, Aris Gaci, Antti Matvere, Marc Aubry, Aurélien Bore, David Gilot, Aurélie Goyenvalle, Rémy Pedeux
The paper identifies WDR91 as a promoter of ASO activity in melanoma through a CRISPR screen, highlighting its role in endosomal maturation and ASO efficacy.
Molecular Therapy — Nucleic Acids · May 24, 2025Peer-reviewedMolecular Biology