Grant McFadden

This paper investigates a new MYXV isolate, MYXV-Tol, which causes atypical myxomatosis in European rabbits and hares, showing it has evolved to cause a more severe, acute disease with distinct clinical features.

This study identifies divergence in poxvirus E3-like proteins and shows that Leporipoxviruses induce necroptosis while Orthopoxviruses inhibit it.

This study analyzes poxvirus genome architecture across the family, finding correlations between genome size, coding density, GC-content, and protein distribution, with implications for viral evolution and biology.

The paper identifies a poxvirus effector that triggers an NF-κB response by disrupting anti-viral complexes, revealing a novel ETI pathway.

This study shows that PEGSerp-1, a virus-derived serpin, improves survival and reduces immunothrombotic damage in a mouse colitis model.