Author

Bertram L. Jacobs

Arizona State UniversityORCID 0000-0002-9529-8107Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:multiome· 1 Approach:statistical model· 1

Frequent Co-Authors

James Bonner· 2 shared Arkadiy I. GarberiD· 1 shared Grant McFaddeniD· 1 shared Jacqueline WilliamsiD· 1 shared Junior A. EnowiD· 1 shared Kristen W. LynchiD· 1 shared Masmudur M. RahmaniD· 1 shared Matthew P. TraceyiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersImmunology

James Bonner

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Nonsense-mediated decay controls a negative feedback loop in innate immune sensing

Simon Boudreault, Yahira Rivera-Lopez, Max Ferretti, Matthew P. Tracey, James Bonner, Bertram L. Jacobs, Kristen W. Lynch

The paper shows that dsRNA sensing inhibits NMD, forming a negative feedback loop that limits dsRNA-mediated immune responses.

Proceedings of the National Academy of Sciences · Jan 9, 2026Peer-reviewedImmunology

Evolutionary Variation of Poxvirus Genome Architecture

Junior A. Enow, Arkadiy I. Garber, Bertram L. Jacobs, Grant McFadden, Masmudur M. Rahman

This study analyzes poxvirus genome architecture across the family, finding correlations between genome size, coding density, GC-content, and protein distribution, with implications for viral evolution and biology.

bioRxiv · Oct 8, 2025 · PreprintMicrobiology

Regulation of Necroptosis and the Type Interferon Response by Monkeypox/mpox Virus.

Jacqueline Williams, James Bonner, Bertram L. Jacobs

This study investigates how MPXV evades necroptosis and the type I interferon response by modifying key proteins, showing that it inhibits necroptosis through RIPK3 degradation and MLKL inhibition, and is sensitive to interferon via ZBP1, RIPK3, and MLKL.

bioRxiv · Oct 31, 2024 · PreprintMolecular Biology