ImmunologybioRxiv
Direct contact between iPSC-derived macrophages and hepatocytes drives reciprocal acquisition of Kupffer cell identity and hepatocyte maturation
Christopher Lee, Farah Tasnim, Xiaozhong Huang…·Florent Ginhoux
This study shows that co-culturing iPSC-derived macrophages with hepatocytes enhances macrophage maturation and hepatocyte function through direct cell-cell contact.