Cell BiologyNature MethodsPeer-reviewed
Dose-Efficient Cryo-Electron Microscopy for Thick Samples using Tilt-Corrected Scanning Transmission Electron Microscopy, Demonstrated on Cells and Single Particles
Yue Eric Yu, Katherine A. Spoth, Michael Colletta…·Lena Fitting Kourkoutis
This paper introduces tilt-corrected bright-field scanning-TEM (tcBF-STEM) for cryo-EM, showing improved contrast and efficiency for thick samples, with a subnanometer resolution SPA map of a virus-like particle.
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