Author

Charlie Dubbeldam

New York Structural Biology CenterORCID 0009-0003-7821-5087Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Organism:E. coli· 1 Assay:electronic health records· 1 Assay:protein sequence· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Jake D. JohnstoniD· 2 shared Mohammadreza ParaaniD· 2 shared Aaron K. Kidane· 1 shared Alex de MarcoiD· 1 shared Alex J. NobleiD· 1 shared Allie C. ObermeyeriD· 1 shared Aygul IshemgulovaiD· 1 shared Daniel SerwasiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiophysics

Jake D. JohnstonORCID

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3 papers

Recent·Most cited

Cell BiologyNature MethodsPeer-reviewedSep 23, 2025

Dose-Efficient Cryo-Electron Microscopy for Thick Samples using Tilt-Corrected Scanning Transmission Electron Microscopy, Demonstrated on Cells and Single Particles

Yue Eric Yu, Katherine A. Spoth, Michael Colletta…·Lena Fitting Kourkoutis

This paper introduces tilt-corrected bright-field scanning-TEM (tcBF-STEM) for cryo-EM, showing improved contrast and efficiency for thick samples, with a subnanometer resolution SPA map of a virus-like particle.

60 citationstop 1%

bacteria (other)cryo-EM

𝕏 PostBluesky

BiophysicsBiomacromoleculesPeer-reviewedSep 3, 2025

Cationic amino acid identity and net charge influence condensate properties in E. coli

Aaron K. Kidane, Jacob R. Rosenfeld, Jake D. Johnston…·Allie C. Obermeyer

This study shows that cationic amino acid identity and net charge affect condensate properties in E. coli, with arginine promoting better encapsulation and stability than lysine.

1 citation

E. coliprotein sequence

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJan 23, 2024

CryoCycle your grids: Plunge vitrifying and reusing clipped grids to advance cryoEM democratization

Viacheslav Serbynovskyi, Jing Wang, Eugene Y. D. Chua…·Alex J. Noble

This paper introduces CryoCycle, a method for blotting, vitrifying, and reusing clipped cryoEM grids to reduce costs and improve access to cryoEM.

2 citations

electronic health recordsexperimental assay

𝕏 PostBluesky