ImmunologybioRxivPreprint
Ability of mycobacterial pathogens to establish a persistent infection is lost by deletion of a single gene, rel, regulator of the stringent response
Asmaa H. Mahmoud, Gaber S. Abdellrazeq, Lindsay M. Fry…·Kun Taek Park
The paper shows deletion of the rel gene in mycobacterial pathogens prevents persistent infection and impairs CD8 T cell responses in cattle, but not the timing or cytokine expression of the response.
DOI 10.1101/2024.01.10.575042