Author

Lei Fang

New York UniversityORCID 0000-0002-2582-4845Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Chunyuan JiniD· 2 shared Danqi CheniD· 2 shared Adrian T. GrzybowskiiD· 1 shared Alexandru OdainiciD· 1 shared Andrei M. Komarov· 1 shared Aparna Sahajan· 1 shared Beatrix R. BradfordiD· 1 shared Bingqing Zhang· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersMolecular Biology

Chunyuan JinORCID

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3 papers

Recent·Most cited

NULISA: a novel proteomic liquid biopsy platform with attomolar sensitivity and high multiplexing

Wei Feng, Joanne C. Beer, Qinyu Hao, Ishara S. Ariyapala, Aparna Sahajan, Andrei M. Komarov, Katie Cha, Mason Moua, Xiaolei Qiu, Xiaomei Xu, Shweta Iyengar, Thu Yoshimura, Rajini Nagaraj, Li Wang, Ming Yu, , Xiao-Jun Ma

NULISA is a proteomic platform with attomolar sensitivity and high multiplexing, enabling detection of low-abundance proteins in liquid biopsies.

Nature Communications · Nov 9, 2023Peer-reviewedGenomics

Potential Functions of Histone H3.3K56 Acetylation in Mammals

Lei Fang, Danqi Chen, Jingzi Zhang, Kai Li, Beatrix R. Bradford, Chunyuan Jin

This study investigates the role of H3.3K56 acetylation in mammals using mutants, showing its importance in chromosome segregation and cell division.

Epigenetics · Apr 27, 2021Peer-reviewedMolecular Biology

Polyadenylation of Histone H3.1 mRNA Promotes Cell Transformation by Displacing H3.3 from Gene Regulatory Elements

Danqi Chen, Qiao Yi Chen, Zhenjia Wang, Yusha Zhu, Thomas Kluz, Wuwei Tan, Jinquan Li, Feng Chi Wu, Lei Fang, Xiaoru Zhang, Rong‐Quan He, Steven Shen, Hong Sun, Chongzhi Zang, Chunyuan Jin, Max Costa

The paper shows that polyadenylation of H3.1 mRNA displaces H3.3 from gene regulatory elements, leading to cell transformation and genomic instability.

iScience · Jan 1, 2019Peer-reviewedMolecular Biology