BioinformaticsbioRxivPreprint
Single cell and spatial alternative splicing analysis with long read sequencing
Yuntian Fu, Heon Seok Kim, Jenea I. Adams…·Nancy Ruonan Zhang
The paper develops Longcell, a statistical framework for accurate isoform quantification in single cell and spatial long-read sequencing data, revealing intra-cell splicing heterogeneity and validating regulatory targets.
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