Allison E. Schloop

This study visualizes Cactus dynamics in Drosophila embryos using LlamaTag and optical techniques, revealing nuclear localization and biophysical parameters of the NF-κB pathway.

The paper investigates how the Dorsal morphogen gradient remains robust to variations in maternal dorsal mRNA dosage, identifying three mechanisms that contribute to this robustness.

The paper demonstrates that the Dorsal/NF-κB morphogen gradient in Drosophila embryos is established via shuttling by Cactus/IκB, enabling viability of embryos with one maternal copy of dorsal.