Ernesto Abel‐Santos

The paper screens bile salt analogs to identify compounds that reduce lipid accumulation in liver cells and inhibit C. difficile spore germination, offering potential dual therapy for MASLD and CDI.

This study examines the role of dipicolinic acid (DPA) in Bacillus anthracis spore biology and cytotoxicity, finding that DPA is essential for spore viability and dormancy but not required for macrophage virulence.

This study identifies nutrient requirements for different stages of the Bd life cycle, showing specific amino acids and nitrogen sources are critical for progression and completion of the differentiation cycle.

The paper investigates how sexual dimorphism and estrous cycle affect C. difficile infection prophylaxis in two rodent models.

This paper develops a murine model of antibiotic-associated S. aureus gastrointestinal infections, showing sexual dimorphism and diet-dependent severity.