Author

Jana Helsen

Stanford MedicineORCID 0000-0002-2637-7047Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:development & morphogenesis· 1 Approach:statistical model· 1 Organism:yeast· 1

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Gautam DeyiD· 1 shared Gavin J. SherlockiD· 1 shared Kausthubh RamachandraniD· 1 shared

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2025-2025 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperEvolutionary Biology

Gautam DeyORCID

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1 paper

Recent·Most cited

Evolutionary BiologyNaturePeer-reviewedNov 26, 2025

Centromeres evolve progressively through selection at the kinetochore interface

Jana Helsen, Kausthubh Ramachandran, Gavin J. Sherlock, Gautam Dey

The paper investigates how new centromeres evolve and become fixed in budding yeast by analyzing 138 species and 2,500 isolates, showing that kinetochore interface constraints influence centromere evolution.

12 citationstop 3%

yeaststatistical model

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