Author

Kausthubh Ramachandran

Heidelberg UniversityORCID 0000-0002-6221-8166Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 3 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:chromatin & epigenetic regulation· 3 Approach:experimental assay· 3 Organism:Drosophila· 2 Organism:human· 2 Organism:yeast· 2 Research Focus:cell signaling & trafficking· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

Gautam DeyiD· 3 shared Alessia LoffredaiD· 2 shared Ashutosh KumariD· 2 shared Daria MaslennikovaiD· 2 shared Harry J. M. BairdiD· 2 shared Madhav JagannathaniD· 2 shared Stefano VanniiD· 2 shared Ulrike KutayiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCell Biology

Gautam DeyORCID

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4 papers

Recent·Most cited

A bacterial nucleolus for cold adaptation

Michelle Jennifer Gut, Kerstin Dörner, Sebastian Abegg, Nusrat S. Qureshi, Kausthubh Ramachandran, Alexia Ferrand, Alexander Schmidt, Rūta Prakapaitė, Tom A. Williams, Olivier Duss, Maria Hondele

The paper identifies a nucleolus-like condensate in E. coli that forms during cold adaptation to enhance ribosome biogenesis.

bioRxiv · Sep 18, 2026 · PreprintCell Biology

A conserved mechanism of membrane fusion in nuclear pore complex assembly

Jonas S. Fischer, Matthias Wojtynek, Ashutosh Kumar, Harry J. M. Baird, Kateřina Radilová, Daria Maslennikova, Kausthubh Ramachandran, Anna N. Becker, Arantxa Agote‐Arán, Alessia Loffreda, Annemarie Kralt, Madhav Jagannathan, Gautam Dey, Ulrike Kutay, Stefano Vanni, Karsten Weis

This study identifies Brl1 and Brr6 as conserved fusogens mediating membrane fusion during NPC assembly in eukaryotes.

Molecular Cell · Jul 9, 2026Peer-reviewedCell Biology

Centromeres evolve progressively through selection at the kinetochore interface

Jana Helsen, Kausthubh Ramachandran, Gavin J. Sherlock, Gautam Dey

The paper investigates how new centromeres evolve and become fixed in budding yeast by analyzing 138 species and 2,500 isolates, showing that kinetochore interface constraints influence centromere evolution.

Nature · Nov 26, 2025Peer-reviewedEvolutionary Biology

Dystonia-associated Torsins sustain CLCC1 function to promote membrane fusion of the nuclear envelope for NPC biogenesis

Daria Maslennikova, Harry J. M. Baird, Alessia Loffreda, Kausthubh Ramachandran, Ashutosh Kumar, Jelmi uit de Bos, Caroline Ashiono, Katharina Frischer-Ordu, Naemi Luithle, Federico Uliana, Gautam Dey, Stefano Vanni, Madhav Jagannathan, Ulrike Kutay

This study identifies CLCC1 as a Torsin1A binding partner essential for nuclear envelope membrane fusion during NPC biogenesis, showing its therapeutic potential for DYT1 dystonia.

bioRxiv · Nov 7, 2025 · PreprintCell Biology