NeurosciencebioRxivPreprint
An in vitro neurogenetics platform for precision disease modeling in the mouse
Daniel Cortés, Mélanie Escudero, Austin C. Korgan…·Martín F. Pera
This paper develops a cross-species platform to model human disease using genetically diverse mouse and human stem cells, showing that DYRK1A loss of function effects vary with genetic background.
DOI 10.1101/2022.01.21.477242