David Moi

This paper reports on the fourth CAFA challenge, showing improvements in Gene Ontology term prediction but highlighting challenges in new evaluation settings.

The paper introduces a structure-informed phylogenetic framework to study the evolutionary diversification of RRNPPA quorum sensing receptors in gram-positive bacteria and their viruses.

This study shows CDK4 inhibits TNBC cell migration by phosphorylating Myo9b, which suppresses RhoA signaling, and suggests targeting Myo9b-RhoA could improve CDK4/6 inhibitor therapy.

FastOMA scales orthology inference to handle large genome datasets efficiently while maintaining accuracy.

The paper introduces a phylogenetic profiling method using graph neural networks to reconstruct protein interactions across time, showing improved performance over traditional methods.

HogProf is a scalable phylogenetic profiling method that identifies genes involved in sexual reproduction by comparing gene presence/absence across eukaryotic genomes.