Cell BiologybioRxivPreprint
CDK4 Restricts Triple-Negative Breast Cancer Cell Migration via Phosphorylation-Driven Activation of Myo9b RhoGAP Function
Kanishka Parashar, Laia Simó‐Riudalbas, Arianna Ravera…·Lluis Fajas A
This study shows CDK4 inhibits TNBC cell migration by phosphorylating Myo9b, which suppresses RhoA signaling, and suggests targeting Myo9b-RhoA could improve CDK4/6 inhibitor therapy.
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