Multi-scale Assessment of Brain Blood Volume and Perfusion in the APP/PS1 Mouse Model of Amyloidosis
Leon P. Munting, Marc P. P. Derieppe, Lenard M. Voortman, Artem Khmelinskii, Ernst Suidgeest, Lydiane Hirschler, Emmanuel Barbier, Baudouin Denis de Senneville, Louise van der Weerd
This study assesses brain vascular structure and function in APP/PS1 mice with amyloid β plaques, finding no differences in cerebral blood volume or flow compared to wild-type controls.
bioRxiv · Jul 1, 2022 · PreprintNeuroscience