Author

Leon P. Munting

Leiden University Medical CenterORCID 0000-0002-2352-4451Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:imaging· 3 Organism:mouse· 3 Research Focus:cell type annotation· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Baudouin Denis de SennevilleiD· 2 shared Brian J. BacskaiiD· 2 shared Emmanuel BarbieriD· 2 shared Lydiane HirschleriD· 2 shared Alyssa RussiD· 1 shared Artem KhmelinskiiiD· 1 shared Christian T. FarrariD· 1 shared Corinne A. AugeriD· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Baudouin Denis de SennevilleORCID

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3 papers

Recent·Most cited

Loss of spontaneous vasomotion precedes impaired cerebrovascular reactivity and microbleeds in a mouse model of cerebral amyloid angiopathy

Mariel G. Kozberg, Leon P. Munting, Lee H Maresco, Corinne A. Auger, Maarten L van den Berg, Baudouin Denis de Senneville, Lydiane Hirschler, Jan M. Warnking, Emmanuel Barbier, Christian T. Farrar, Steven Mark Greenberg, Brian J. Bacskai, Susanne J. van Veluw

bioRxiv · Apr 26, 2024 · PreprintNeuroscience

Hyperactive somatostatin interneurons near amyloid plaque and cell-type-specific firing deficits in a mouse model of Alzheimer's disease

Moustafa Algamal, Alyssa Russ, Morgan R. Miller, Steven S. Hou, Megi Maci, Leon P. Munting, Qiuchen Zhao, Dmitry Gerashchenko, Brian J. Bacskai, Ksenia V. Kastanenka

The paper investigates firing rate changes in inhibitory interneurons near amyloid plaques in an Alzheimer's mouse model, finding hyperactivity in somatostatin-expressing interneurons and hypoactivity in parvalbumin-expressing interneurons.

Communications Biology · Dec 2, 2022Peer-reviewedNeuroscience

Multi-scale Assessment of Brain Blood Volume and Perfusion in the APP/PS1 Mouse Model of Amyloidosis

Leon P. Munting, Marc P. P. Derieppe, Lenard M. Voortman, Artem Khmelinskii, Ernst Suidgeest, Lydiane Hirschler, Emmanuel Barbier, Baudouin Denis de Senneville, Louise van der Weerd

This study assesses brain vascular structure and function in APP/PS1 mice with amyloid β plaques, finding no differences in cerebral blood volume or flow compared to wild-type controls.

bioRxiv · Jul 1, 2022 · PreprintNeuroscience