GenomicsbioRxivPreprint
Disentangling polymer confinement from specific-folding interactions reveals the drivers of E. coli chromosome organization
Pourya Delafrouz, Tanya Nesterova, Frances E. Harris…·J C Liang
The paper develops a polymer simulation framework to distinguish specific-folding interactions from polymer compaction in E. coli, revealing SFIs shape chromosome organization and gene expression.