Systems BiologybioRxivPreprint
Network-scale disruption of RNA-protein interactions by a bioaccumulating small-molecule drug
Xiaoteng Jiang, Simone Mozzachiodi, Indra Roux…·Kiran Raosaheb Patil
This study shows that the antidepressant duloxetine disrupts RNA-protein interactions in both human and bacterial cells, revealing a new mechanism of drug action.
DOI 10.64898/2026.07.23.740326